thats spyware buddy, a virus. im surprised you cant get in via safe mode but theres still plenty of ways to fix it.
what happens when you try safe mode? does it just hang? or seem to hang?
there are lots of tools out there to get you out of that trap, may take a few minutes, may take a few hours depends on if you have important data and settings/passwords etc.
if you are really stuck, ill have a look at them for you but you'll have to drop them off at mine, if thats ok, and leave them with me? either that, or i can send you some usefull tools if you like to tinker?
if you can get the laptops into windows, then thats a start, i can try a few fixes remotely for you.
when you boot the laptop, do the F8 thing, but try "last known good configuration", sometimes that actually does work. failing that, try safe mode but leave it for ten minutes or so, see if it eventually goes in. if it does, you can either choose to restore the laptop, or run some AV tools to remove the crap or create a new profile...lots you can do.